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Tuesday, September 26, 2017

DNA Series: (1): Flawed DNA testing: (False positives do happen); Chen Long-Qi, Taiwon; Writer Kristen Brown describes how bad DNA tests can lead to false convictions - and provides a very good example, in Gizmodo..."The thing is, it’s not always that simple. Most people think of DNA testing as a monolithic, infallible technique. But there are many different kinds of tests—and many different ways of interpreting them. Sometimes, somewhere between the process of collecting evidence at the scene and processing it in the lab, something goes awry."..."Michael Coble, a forensic scientist at the National Institute of Standards and Technology told Gizmodo that closer examination might have allowed the forensic scientists in Taiwan to tell whether the DNA mixture seemed to be largely from one suspect, but otherwise there are limits from the information to be gleaned. “Often times any DNA evidence gets the seal of approval, but it’s really the interpretation that matters,” he said. In a 2013 survey the National Institute of Standards and Technology, which Coble works for, asked 108 labs to interpret a made-up DNA sample with four people in it. They also provided the DNA profile of a fake suspect who wasn’t included in the sample. Seventy percent of the labs found the fake suspect to be a match."..."In forensic science, DNA evidence is gradually attracting more skepticism, and scrutiny to ensure that the conditions under which it was collected and processed were sound. In one 2008 study, researchers wrote that there is “a mystical aura of definitiveness often surrounds the value of DNA evidence,” but all DNA evidence is not created equal. DNA evidence can be conclusive, but only when good DNA samples are tested correctly using the appropriate test."


STORY:  "When Bad DNA Tests Lead to False Convictions by reporter Kristen V.  Brown. published by Gizmodo on September 25, 2017." (Kristen Brown is a senior writer at Gizmodo. Gizmodo is   a design, technology, science and science fiction website that also writes articles on politics.)

GIST: "If you’ve ever watched a prime-time crime drama like CSI, you know that DNA evidence is often the linchpin that makes a case. Match a suspect’s DNA to DNA found at the scene of a crime and it’s certain they’re the culprit. The thing is, it’s not always that simple. Most people think of DNA testing as a monolithic, infallible technique. But there are many different kinds of tests—and many different ways of interpreting them. Sometimes, somewhere between the process of collecting evidence at the scene and processing it in the lab, something goes awry. For Chen Long-Qi, a bad DNA test derailed his life. It was early in the morning on May 25th, 2009 and Chen was hanging out in a Taiwan warehouse he rented for work, drinking with friends. At around three in the morning, they were joined by two women. According to Chen and his lawyers, Chen left shortly after to pick up his wife from work, and sometime between 4 and 6 a.m., the two women were raped. While the victims had not accused Chen of rape and no one had placed Chen at the scene when the assaults took place, he was ultimately convicted and sentenced to four years in prison. DNA evidence had linked him to the crime. Five years later, Chen was exonerated when a second DNA test that found he was not a match after all. In the years he lived as a convicted rapist, he had lost his wife, his business and most of his life. He refused to go to prison, living instead a lonely life as a fugitive, overcome by depression and shame. Chen was what’s known as a coincidental match. Investigators originally tested 17 genetic markers on the Y-chromosome from a mixture of several people’s DNA found at the crime scene, and his DNA was a match. But when they tested a larger number of markers, the match didn’t hold up. Chen’s DNA, it turned out, was not evidence of a crime, but instead evidence of a statistical anomaly that we rarely consider when assessing DNA evidence: that false positives do happen. “All DNA [evidence] is not the same and that’s very hard to explain people,” said Greg Hampikian, a Boise State University professor and director of the Idaho Innocence Project who assisted with exonerating Chen. “Even the experts don’t understand all the time.”......... DNA can be incontrovertible proof that a crime has been committed—or in the case of the many exonerated thanks to DNA testing, proof that it wasn’t. But in Chen’s case, the DNA evidence that mistakenly matched him to the crime was weighted more heavily the testimonies suggesting he was innocent. To understand how that happened, it’s important to understand a bit more about how, exactly, labs match DNA samples. Forensic analysts don’t examine a suspect’s entire genome, but rather a few key places on it where populations are typically diverse, referred to as “markers.” In Chen’s case, the lab examined 17 different Y-chromosome markers. However, this particular Y-chromosome test is not as specific as the most common forensic DNA testing, autosomal short tandem repeat testing, or STR. Both tests look at what’s known as short tandem repeats, genetic locations on a person’s genome that contain a snippet of DNA that is repeated multiple times. The number of those repeats at any location can vary greatly from person-to-person. But whereas the Y-chromosome test looks only at 17 positions on one chromosome, the 13 marker test looks at 13 sites across multiple chromosomes, greatly diminishing the odds of an accidental match. The odds that any two people (except identical twins) will match at all 13 markers in an autosomal STR test is somewhere around 1 in a billion. According to Hampikian, many crime labs still use the test that mistakenly implicated Chen, though he said some labs are gradually gravitating towards the 23-marker Y-chromosome test that eventually exonerated him. In another case that illustrates the powerful effect of DNA evidence, Hampikian used DNA evidence to help exonerate Christopher Tapp, a man who until this spring had been in prison since 1998 serving a 25-years-to-life sentence for murder, though his DNA did not match the crime scene sample...........According to calculations later done by Hampikian and his team, there was a 1 in 741 chance that Chen would match the DNA in question—meaning the DNA on that underwear could hypothetically match thousands of different people in a city of 23 million. The crime lab that ran the test concluded that Chen “or men who share the same paternal line cannot be excluded” as suspects. On this evidence, Chen was convicted of gang rape and sentenced to prison in 2012. The two other men were also a match, and were convicted.  Chen refused to go to prison, telling his attorneys that he would not “voluntarily walk into jail for something I did not do.” He also contacted the Taiwan Association for Innocence, which immediately began working on an appeal, seeing obvious flaws in Chen’s conviction. They argued for the DNA to be retested, this time using a test that looks at 23 genetic markers instead of 17. Of those six new genetic markers included in the new test, Chen was only a match for four. The new evidence excluded him as a possible source for DNA found in the mixed sample. What’s more, all of the genetic markers in the sample could be explained by the other two men who were convicted. On that evidence, the court granted a new trial and overturned his conviction. Dan Krane, an expert in DNA evidence at Wright State University, told Gizmodo that in his opinion, the DNA evidence from Chen’s case should have never been used in the first place, because it was a mixture of several people’s DNA. “There is no accepted, reliable way of attaching a statistical weight to a mixed YSTR DNA test,” he said. “As soon as you see it’s mixed, you have to throw up your hands and say, ‘Well, that’s too bad.’ That would have solved the problem right out of the gate here.” Michael Coble, a forensic scientist at the National Institute of Standards and Technology told Gizmodo that closer examination might have allowed the forensic scientists in Taiwan to tell whether the DNA mixture seemed to be largely from one suspect, but otherwise there are limits from the information to be gleaned. “Often times any DNA evidence gets the seal of approval, but it’s really the interpretation that matters,” he said. In a 2013 survey the National Institute of Standards and Technology, which Coble works for, asked 108 labs to interpret a made-up DNA sample with four people in it. They also provided the DNA profile of a fake suspect who wasn’t included in the sample. Seventy percent of the labs found the fake suspect to be a match. When Gizmodo reached out to the FBI, the agency said that while it does rely on DNA mixtures as evidence, it only does so if a crime lab can pick out one primary person who contributed to a sample. (The FBI also confirmed that its labs still use the 17-marker Y-STR test used in the case against Chen.) In a new case study of Chen’s case published in the journal Forensic Science International: Genetics, Hampikian argues that such evidence should only be used to exclude suspects, not to charge or convict them. Krane said it should be thrown out altogether. “DNA profiling should be binary,” Krane said. “There shouldn’t be a gray area.” Especially when it’s someone’s life on the line. “I think there are maybe a hundred experts who get it and thousands who don’t,” said Krane. “And there [are] prosecutors who don’t want to understand. And I think there’s an awful lot of defense attorneys whose eyes glaze over when DNA is mentioned. It’s hard enough to teach this in a classroom.” Ballistics, fingerprinting, and arson analysis were all once considered solid scientific evidence designed to extract the potential for human bias in investigation. Today, it is well-established that the results of those methodologies are not always sound. In forensic science, DNA evidence is gradually attracting more skepticism, and scrutiny to ensure that the conditions under which it was collected and processed were sound. In one 2008 study, researchers wrote that there is “a mystical aura of definitiveness often surrounds the value of DNA evidence,” but all DNA evidence is not created equal. DNA evidence can be conclusive, but only when good DNA samples are tested correctly using the appropriate test. DNA’s mystical hold over public imagination, Hampikian said, should make all of us very uncomfortable. Chen, Hampikian said, is one of the few cases that caught the attention of experts like him looking to right the wrongs of DNA testing. “The way that we rely on tests has to be reevaluated constantly,” he said. “We are making mistakes today and we won’t know about them for a long time.”

Read the entire story at:

https://gizmodo.com/when-bad-dna-tests-lead-to-false-convictions-1797915655

 PUBLISHER'S NOTE: I am monitoring this case/issue. Keep your eye on the Charles Smith Blog for reports on developments. The Toronto Star, my previous employer for more than twenty incredible years, has put considerable effort into exposing the harm caused by Dr. Charles Smith and his protectors - and into pushing for reform of Ontario's forensic pediatric pathology system. The Star has a "topic" section which focuses on recent stories related to Dr. Charles Smith. It can be found at: http://www.thestar.com/topic/charlessmith. Information on "The Charles Smith Blog Award"- and its nomination process - can be found at: http://smithforensic.blogspot.com/2011/05/charles-smith-blog-award-nominations.html Please send any comments or information on other cases and issues of interest to the readers of this blog to: hlevy15@gmail.com. Harold Levy; Publisher; The Charles Smith Blog.









Posted by Harold Levy at Tuesday, September 26, 2017
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About Me

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Harold Levy
Two Blogs Now: The Charles Smith Blog; The Selfless Warriors Blog: I created the Charles Smith Blog in 2007 after I retired from The Toronto Star to permit me to keep digging into the story of the flawed pathologist and the harm he had done to so many innocent parents and caregivers, and to Ontario’s criminal justice system. Since then it has taken new directions, including examinations of other flawed pathologists, flawed pathology, and flawed science and technology which has marred the quality of justice in courtrooms around the world. On International Wrongful Conviction Day in 2024, I was thrilled to have the Blog recognized by Innocence Canada, when I was presented with the, "Rubin Hurricane Carter Champion of Justice Award." The heart of the Blog is my approach to following cases which raise issues in all of these areas - especially those involving the death penalty. I have dedicated 'The Selfless Warrior Blog’ (soon to appear) to those exceptional individuals who have been ripped out of their ordinary lives by their inability to stand by in the face of a glaring miscarriage of justice. They are my ’Selfless Warriors.’ Enjoy!
View my complete profile
 

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